subject: Computational Biology / Methods

Total is 2 Results
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PFP


Daisuke Kihara, Meghana Chitale, Troy Hawkins


BACKGROUND: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of proteins, and gene expression. The ability of biologists to analyze and interpre...

Biochemistry Bioinformatics Computational Biology / Methods Genetic Molecular Biosciences Proteins / Metabolism

Limitations and Potentials of Current Motif Discovery Algorithms


Bin Li, Daisuke Kihara, Jianjun Hu


Computational methods for de novo identification of gene regulation elements, such as transcription factor binding sites, have proved to be useful for deciphering genetic regulatory networks. However, despite the availability of a large number of algorithm...

Algorithms Base Sequence Binding Sites Biochemistry Bioinformatics Computational Biology / Methods DNA/Chemistry DNA/methods Escherichia coli/Genetics Factors/Metabolism Markov Chains Markov Chains Regulatory Sequences Molecular Biosciences Regulon Sequence Alignment Sequence Analysis

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