Mathematica Files: Competitive tuning: competition’s role in setting the frequency-dependence of Ca2+-dependent proteins

10.4231/R7154F7Q

Daniel Romano , Matthew C Pharris , Neal Patel , Tamara Kinzer-Ursem

09/08/2017

We study the competition among seven well-studied neuronal proteins for their common binding partner, calmodulin. We find that competition narrows and shifts the range over which proteins can be activated.

Biomedical Engineering Calcineurin Calmodulin Computational Biology Mathematica Signal Transduction