Threading Without Optimizing Weighting Factor for the Scoring Function Proteins

10.4231/D3PK0719W

Daisuke Kihara, David Yifeng

02/14/2013

Optimizing weighting factors for a linear combination of terms in a scoring function is a crucial step for success in developing a threading algorithm. Usually weighting factors are optimized to yield the highest success rate on a training dataset, and the...

Algorithms Biochemistry Bioinformatics databases Molecular Biosciences Protein Proteins / chemistry