subject: Neuroscience creator: Matthew C Pharris type: dataset
Total is 4 Results
A Multi-state Model of the CaMKII Holoenzyme using MCell 3.3
10.4231/MV0Z-8Z57
Matthew C Pharris
,
Tamara L Kinzer-Ursem
07/29/2019
This model uses a specialized rule-based syntax in MCell 3.3 to model the twelve-subunit CaMKII holoenzyme without inducing combinatorial explosion. The model allows us to explore the regulation of CaMKII activation and autophosphorylation.
Biomedical Engineering Calcium Calmodulin Computational Modeling Kinase Neuroscience Protein Signaling Rule-Based Modeling Synaptic Plasticity
Competitive Tuning of Ca2+/Calmodulin-Activated Proteins Provides a Compensatory Mechanism for AMPA Receptor Phosphorylation in Synaptic Plasticity
10.4231/R7VX0DS0
Matthew C Pharris
,
Tamara L. Kinzer-Ursem
07/30/2018
Code for the basic 4-state competitive binding model that builds on previous work by incorporating an additional competitor for calmodulin along with a number of downstream proteins. Also include is sample code for global sensitivity analysis...
A Multi-state Model of the CaMKII Holoenzyme using MCell 3.3
10.4231/MBPK-D277
Matthew C Pharris
,
Tamara L Kinzer-Ursem
03/11/2019
This model uses a specialized rule-based syntax in MCell 3.3 to model the twelve-subunit CaMKII holoenzyme without inducing combinatorial explosion. The model allows us to explore the regulation of CaMKII activation and autophosphorylation.
Biomedical Engineering Calmodulin Computational Modeling Neuroscience Protein Signaling
Competitive Tuning of Ca2+/Calmodulin-Activated Proteins Provides a Compensatory Mechanism for AMPA Receptor Phosphorylation in Synaptic Plasticity
10.4231/R7ST7N11
Matthew C Pharris
,
Tamara L. Kinzer-Ursem
02/16/2018
Code for the basic 4-state competitive binding model that builds on previous work by incorporating an additional competitor for calmodulin along with a number of downstream proteins. Also include is sample code for global sensitivity analysis...
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