PURR Registry

Circadian Disruption Decreases Gluconeogenic Flux

10.4231/JB0Q-DR06

11/01/2022

The data provide here are 13C enrichment ratios of amino acids following incubation in [U-13C] propionate to evaluate carbon flux towards glucose or tricarboxylic acid (TCA) cycle intermediates. These data are presented and discussed in a manuscript.

Animal Sciences circadian dairy cow gluconeogenesis liver Stable Isotope Tricarboxylic acid cycle

Fluxomics Combined with Shotgun Proteomics Reveals a Differential Response of Bovine Kidney Cells to Extracellular Palmitic and α-Linolenic Acid

10.4231/V1F7-GA98

Linda Marie Beckett , Theresa M. Casey

09/18/2024

Pyruvate carboxylase (PC) catalyzes the formation of the oxaloacetate a key TCA cycle intermediate and gluconeogenic substrate. Altering saturated to unsaturated fatty acid ratio alters PC expression, suggesting a central role in mediating carbon flow thr

MDBK cells metabolic flux palmitic acid α-linolenic acid

Supplemental Tables and Figures for Effect of circadian system disruption on the concentration and daily oscillations of cortisol, progesterone, melatonin, serotonin, growth hormone, and core body temperature in periparturient dairy cattle

10.4231/KEHG-RN90

Aridany Suárez Trujillo , Jacquelyn P Boerman , Theresa M. Casey

12/17/2021

Changes in daily fluctuations of body temperature and hormone concentrations, related with reproduction and metabolism, were measured and the strength of circadian rhythms of body temperature, serotonin and cortisol increased between three weeks...

Animal Sciences Cattle circadian clocks cortisol

Molecular signatures of longissimus dorsi muscle are distinct between multiparous dairy cattle with differing prepartum muscle reserves and altered by branched-chain volatile fatty acid supplementation

10.4231/5PEP-Y543

Jacquelyn P Boerman , James Markworth , kgouveia@purdue.edu , lbecket@purdue.edu , Theresa M. Casey

06/20/2024

Differences in prepartum muscle reserves reflect distinct muscle metabolism and branched-chain volatile fatty acid supplementation altered metabolic pathways.

branched-chain volatile fatty acid dairy cattle longissimus dorsi muscle reserves RNA_seq

Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling.

10.4231/8CAA-WS64

Theresa M. Casey

03/25/2021

Circadian disruption increased insulin resistance and decreased mammary development in late gestation cows. The effect of circadian disruption on liver and mammary transcriptomes was measured to understand how it impacted hepatic function and...

Animal Sciences Circadian Rhythm hepatic mammary Periparturient Dairy Cows Transcriptome

Lipidome profiles of postnatal day 2 vaginal swabs reflect fat composition of gilt’s postnatal diet.

10.4231/1ERN-QQ28

Christina Ferreira , KaLynn Harlow , Kara Stewart , Theresa M. Casey , Tiago Sobreira

07/25/2019

We investigated the efficacy of using MRM-profiling of vaginal lipids to differentiate PND 2 vaginal swabs between gilts suckled by sow or fed milk replacer and tested the effect of a lard based supplement on vaginal lipid profiles of gilts.

Animal Sciences Bindley Science Center Biomarker Colostrum Developmental Origins of Health and Disease Gilts Lipidome Swine Vagina

Dry Matter Intake and Beta-Hydroxybutyrate Response in a GTT in Phase Shifted Dairy Cows

10.4231/WJYX-B949

Aridany Suarez Trujillo , Conor John Mccabe , Jacquelyn P Boerman , Theresa M. Casey

12/10/2020

Circadian disruptions in dairy cattle did not affect BHB concentrations in response to an IVGTT at 14 days before expected calving and 7 days in milk. Additionally, there was no effect of disruptions on dry matter intake

Animal Sciences Circadian Rhythm Glucose Tolerance Test Periparturient Dairy Cows

Rest-activity patterns and saliva cortisol rhythms during gestational weeks 22 and 32 and postpartum week 1

10.4231/1WB1-MN86

Aridany Suarez Trujillo , Azza Ahmed , Theresa M. Casey

03/25/2021

24 h rest-activity and saliva cortisol rhythms in primiparous women during pregnancy and postpartum

actigraphy Animal Sciences circadian cortisol gestation primiparous rest-activity

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Total is 8 Results