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Reverse engineering morphogenesis through Bayesian optimization of physics-based models

  • Nilay Kumar, Mayesha Mim, Alexander Dowling, Jeremiah Zartman

    01/23/2025

    Morphogenetic programs coordinate cell signaling and mechanical interactions to shape organs. In systems and synthetic biology, a key challenge is determining optimal cellular interactions for predicting organ shape, size, and function. Physics-based model...

  • Keywords:

    Bayesian optimization morphogenesis mechanotransduction extracellular matrix

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