Reverse engineering morphogenesis through Bayesian optimization of physics-based models

• Nilay Kumar, Mayesha Mim Alexander Dowling, Jeremiah Zartman

  01/23/2025

  Morphogenetic programs coordinate cell signaling and mechanical interactions to shape organs. In systems and synthetic biology, a key challenge is determining optimal cellular interactions for predicting organ shape, size, and function. Physics-based model...

• Keywords:

  Bayesian optimization morphogenesis mechanotransduction extracellular matrix